This research area focuses on the analysis and design of wireless communication systems at the physical layer, with an emphasis on realistic modeling, analytical performance evaluation, and complexity-aware system optimization. The work spans a wide range of wireless technologies, including millimeter-wave and massive MIMO systems, device-to-device and ad hoc networks, centralized and virtualized radio access networks, and emerging architectures such as fluid antenna systems (FAS), reconfigurable intelligent surfaces (RIS), and integrated sensing and communications (ISAC). A unifying theme is the development of tractable analytical frameworks that account for practical impairments—such as interference, blockage, fading correlation, finite network geometries, and computational constraints—while enabling insight-driven design. This research also includes contributions to coding and modulation, noncoherent and network-coded communications, cooperative diversity, relay networks, and frequency-hopping systems, with results that bridge information theory, signal processing, and network-level performance. Collectively, this body of work provides foundational tools for understanding and designing robust, high-performance wireless systems operating in dense, dynamic, and often harsh environments.